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Establish baseline measurements before beginning treatment

For example, C-terminal amides and cyclic imides are targeted by the Cullin-RING ligases FBXO31 and CRBN, respectively 28,29

Natural oils Numerous studies have demonstrated that incorporating natural oils into the diet or using them topically could potentially have therapeutic benefits for UC, as they can modulate the gut microbiota, inhibit inflammation and improve intestinal homeostasis [161]

We acknowledge that clinicians and practices in selected regions could face challenges or benefits as part of the ASM test, but this is necessary to ensure a valid evaluation of the model test